Extragenital and infectious factors may provoke miscarriage

Adverse reproductive outcome before term is a polyetiological pathology associated with demographic crisis. Some adverse outcomes include perinatal and neonatal infant mortality, major morbidity mortality of children under two years, violation psychomotor physical development, cognitive disturbances disability age five. Finding ways to solve these issues remain priority. The research involved female groups. experimental group included 403 women after the involuntary termination pregnancy, premature birth or in case threat miscarriage; control 402 physiological course pregnancy parturient full-term pregnancy. study required application systemic approaches methods including structural, logical, medical statistical analyses. survey revealed more than 20 infectious risk factors 70 extragenital origin. most significant pathologies COVID-19 (36.23 ± 2.29% 14.93 1.78%), herpes type 1 (5.96 1.18% 1.0 0.50%), toxoplasmosis (4.22 1.0% 0.50%) chlamydial infection 0.50 0.35%) groups, respectively (P < 0.01). autoimmune thyroiditis (8.68 1.40% 0.75 0.43%), diabetes mellitus (2.23 0.74% 0%) allergic rhinitis/sinusitis (3.97 0.97% Obtained results will be used development personified risk-oriented model for prevention preterm loss. Keywords: term, pathology, factors,